Healthcare Practitioners
The science
For clinicians
Nest products are formulated around the biology of the developing infant skin microbiome. This page exists for the practitioners who want to understand exactly what's in the product, why it's there, and what the peer-reviewed research says.
Practitioner inquiries
Sample requests, formulation questions, and research resources available on request.
Clark Sather is available to speak directly with practitioners about the formulation science.
Who this page is for
Pediatricians & family physicians
Practitioners recommending daily care products to families of newborns and infants.
Pediatric dermatologists
Specialists advising families on skin barrier health, eczema-prone skin, and microbiome-supportive care.
Lactation consultants & midwives
Practitioners working with families in the newborn period, when the skin microbiome begins establishing.
Naturopathic & integrative practitioners
Clinicians advising families on microbiome-supportive approaches from birth.
NICU & neonatal care teams
Practitioners focused on the most sensitive skin — newborns where every ingredient decision matters.
Infant care researchers
Academics and researchers working in infant microbiome, skin barrier, or early-life health fields.
The biology behind Nest
The microbiome rationale
Why pH matters from day one
The infant skin microbiome begins establishing at birth and continues developing through approximately the first two years of life. During this period the skin surface acidifies from near-neutral toward the healthy range of pH 5.0–5.5 — a range that selectively supports beneficial bacteria while inhibiting pathogenic colonization.
Most conventional baby wipes are formulated at pH 6.5–7.0. Applied six to ten times daily, this repeated alkaline exposure may interfere with the skin's natural acidification process. Nest wipes are formulated at pH 5.0–5.5 — matched to the biology of the process already occurring.
The prebiotic approach
Feeding the bacteria already there
NatureBiome™ combines inulin and alpha-glucan oligosaccharide — two topical prebiotics with distinct mechanisms. Inulin selectively feeds beneficial cutaneous bacteria. Alpha-glucan oligosaccharide supports the balance between commensal and transient bacterial populations on the skin surface.
A prebiotic approach — supporting existing beneficial bacteria rather than introducing new strains — was chosen over probiotics for stability, regulatory clarity, and cosmetic-level claim integrity. No live organisms, no refrigeration requirements, no probiotic survival questions. The prebiotics work with what's already there.
All claims on this page and on Nest packaging are cosmetic-level only. Nest products are not intended to diagnose, treat, cure, or prevent any disease. These statements have not been evaluated by the Food and Drug Administration.
Peer-reviewed anchors
Wipes — formulation at a glance
pH range
5.0 – 5.5
Formulated for comfort. The range where beneficial bacteria thrive.
Total ingredients
15
All disclosed. Full list with function explanations at nestorganic.com/pages/ingredients.
Prebiotic system
NatureBiome™
Inulin + alpha-glucan oligosaccharide. Dual mechanism, topical application.
Preservative system
3-part
Sodium benzoate, sodium levulinate, sodium anisate. Distributed system — no single preservative carries full burden.
Substrate
Bamboo lyocell
Soft, low-friction. No polyester content in wipe substrate.
Absent ingredients
None of the following
No parabens, phthalates, formaldehyde donors, musks, ethanolamines, glycol ethers, siloxanes, or fragrance.
Transparency note
The formulation rationale is grounded in published peer-reviewed research on pH, prebiotic mechanisms, and the developing infant skin microbiome — not on proprietary clinical trials conducted on this specific product.
Practitioner inquiry
Request samples
or ask us anything
We'll respond directly — from Clark or Ana, not from a support team. If you have questions about the formulation the form doesn't cover, just ask in the notes field.
- Product samples available on request
- Full ingredient SDS available
- Direct access to the formulator
- Response within 2 business days
All Nest products are cosmetic products regulated under the FDA Modernization of Cosmetics Regulation Act (MoCRA). These products are not drugs, are not intended to diagnose, treat, cure, or prevent any disease, and carry no therapeutic claims. These statements have not been evaluated by the Food and Drug Administration.
Nest. · P.O. Box 8662, Calabasas, CA 91372 · hello@shopnestorganic.com